HOME HELP CONTACT US SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by LE MAGUERESSE, B. Articles by JEGOU, B. Search for Related Content PubMed Articles by LE MAGUERESSE, B. Articles by JEGOU, B.

Indirect approach (hypotonic treatment) and direct approaches (co-cultures and conditioned media) were used in order to investigate the effects of germ cells from adult rats upon transferrin secretion by Sertoli cell cultures prepared from 20-day-old rats. Removal of germ cells contaminating the Sertoli cell cultures resulted in a significant decrease in transferrin secretion whereas the addition of crude germ cell preparations or of enriched preparations of pachytene spermatocytes, early spermatids and of liver epithelial cells (LEC) markedly stimulated this parameter. Furthermore, spent media of pachytene spermatocytes and of early spermatids, but not of LEC, also stimulated transferrin production. It is concluded that germ cells normally located within the adluminal compartment of the seminiferous tubules may be capable of controlling their own supply of iron via their influence upon transferrin secretion by the Sertoli cells.

This article has been cited by other articles:

				M. G. Yefimova, A. Sow, I. Fontaine, V. Guilleminot, N. Martinat, P. Crepieux, S. Canepa, M.-C. Maurel, S. Fouchecourt, E. Reiter, et al. Dimeric Transferrin Inhibits Phagocytosis of Residual Bodies by Testicular Rat Sertoli Cells Biol Reprod, April 1, 2008; 78(4): 697 - 704. [Abstract] [Full Text] [PDF]

				M. G. Yefimova, J.-C. Jeanny, X. Guillonneau, N. Keller, J. Nguyen–Legros, C. Sergeant, F. Guillou, and Y. Courtois Iron, Ferritin, Transferrin, and Transferrin Receptor in the Adult Rat Retina Invest. Ophthalmol. Vis. Sci., July 1, 2000; 41(8): 2343 - 2351. [Abstract] [Full Text]

				V. Syed, E. Gomez, and N. B. Hecht mRNAs Encoding a von Ebner's-like Protein and the Huntington Disease Protein Are Induced in Rat Male Germ Cells by Sertoli Cells J. Biol. Chem., April 16, 1999; 274(16): 10737 - 10742. [Abstract] [Full Text] [PDF]