| HOME | HELP | CONTACT US | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
The participation of the ovarian steroids and opioid peptides in the suppression of pulsatile LH release during acute fasting was examined in rats. Ovariectomized rats bearing silicone elastomer implants of oestradiol and/or progesterone were fasted for 48 h and subsequently blood samples were taken every 6 min for 3 h. Pulsatile LH release was suppressed after 48 h of fasting in the ovariectomized rats implanted with oestradiol but not in the oil-implanted controls. This suppression was enhanced after the administration of progesterone together with oestradiol.
In a second experiment, ovariectomized rats bearing implants of oestradiol or oil were fasted for 48 h and injected s.c. (2·5 mg/kg body weight) with an opioid antagonist, naloxone hydrochloride, immediately before blood sampling. In the fasted oestradiol-treated ovariectomized rats, naloxone was able to prevent the suppression of pulsatile LH release. In the absence of oestradiol, however, naloxone was without effect on LH release in either the fasted or unfasted animals.
These experiments indicate that the suppression of pulsatile LH release after 48 h of fasting is dependent upon oestradiol and that endogenous opioids are involved in the suppression.
Journal of Endocrinology (1991) 129, 321–328
This article has been cited by other articles:
|
|
 |
|
  S. Sajapitak, K. Iwata, M. Shahab, Y. Uenoyama, S. Yamada, M. Kinoshita, F. Y. Bari, H. I'Anson, H. Tsukamura, and K.-i. Maeda Central Lipoprivation-Induced Suppression of Luteinizing Hormone Pulses Is Mediated by Paraventricular Catecholaminergic Inputs in Female Rats Endocrinology, June 1, 2008; 149(6): 3016 - 3024. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. F. Li, J. S. Kinsey-Jones, A. M. I. Knox, X. Q. Wu, D. Tahsinsoy, S. D. Brain, S. L. Lightman, and K. T. O'Byrne Neonatal Lipopolysaccharide Exposure Exacerbates Stress-Induced Suppression of Luteinizing Hormone Pulse Frequency in Adulthood Endocrinology, December 1, 2007; 148(12): 5984 - 5990. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Yamada, Y. Uenoyama, M. Kinoshita, K. Iwata, K. Takase, H. Matsui, S. Adachi, K. Inoue, K.-I. Maeda, and H. Tsukamura Inhibition of Metastin (Kisspeptin-54)-GPR54 Signaling in the Arcuate Nucleus-Median Eminence Region during Lactation in Rats Endocrinology, May 1, 2007; 148(5): 2226 - 2232. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. A S Reyes, H. Tsukamura, H. I'Anson, M. A. C Estacio, K. Hirunagi, and K.-I. Maeda Temporal expression of estrogen receptor {alpha} in the hypothalamus and medulla oblongata during fasting: a role of noradrenergic neurons. J. Endocrinol., September 1, 2006; 190(3): 593 - 600. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. F. Li, J. E. Bowe, S. L. Lightman, and K. T. O'Byrne Role of Corticotropin-Releasing Factor Receptor-2 in Stress-Induced Suppression of Pulsatile Luteinizing Hormone Secretion in the Rat Endocrinology, January 1, 2005; 146(1): 318 - 322. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. C. Mitchell, X. F. Li, L. Breen, J.-C. Thalabard, and K. T. O'Byrne The Role of the Locus Coeruleus in Corticotropin-Releasing Hormone and Stress-Induced Suppression of Pulsatile Luteinizing Hormone Secretion in the Female Rat Endocrinology, January 1, 2005; 146(1): 323 - 331. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Ohkura, T. Ichimaru, F. Itoh, S. Matsuyama, and H. Okamura Further Evidence for the Role of Glucose as a Metabolic Regulator of Hypothalamic Gonadotropin-Releasing Hormone Pulse Generator Activity in Goats Endocrinology, July 1, 2004; 145(7): 3239 - 3246. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. F. Li, J. E. Bowe, J. C. Mitchell, S. D. Brain, S. L. Lightman, and K. T. O'Byrne Stress-Induced Suppression of the Gonadotropin-Releasing Hormone Pulse Generator in the Female Rat: A Novel Neural Action for Calcitonin Gene-Related Peptide Endocrinology, April 1, 2004; 145(4): 1556 - 1563. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. D. Sullivan and S. M. Moenter {gamma}-Aminobutyric Acid Neurons Integrate and Rapidly Transmit Permissive and Inhibitory Metabolic Cues to Gonadotropin-Releasing Hormone Neurons Endocrinology, March 1, 2004; 145(3): 1194 - 1202. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Abizaid, D. Kyriazis, and B. Woodside Effects of leptin administration on lactational infertility in food-restricted rats depend on milk delivery Am J Physiol Regulatory Integrative Comp Physiol, January 1, 2004; 286(1): R217 - R225. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Matsuwaki, E. Watanabe, M. Suzuki, K. Yamanouchi, and M. Nishihara Glucocorticoid Maintains Pulsatile Secretion of Luteinizing Hormone under Infectious Stress Condition Endocrinology, August 1, 2003; 144(8): 3477 - 3482. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. W. Hill and J. E. Levine Abnormal Response of the Neuropeptide Y-Deficient Mouse Reproductive Axis to Food Deprivation But Not Lactation Endocrinology, May 1, 2003; 144(5): 1780 - 1786. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. I. Williams, D. L. Helmreich, D. B. Parfitt, A. Caston-Balderrama, and J. L. Cameron Evidence for a Causal Role of Low Energy Availability in the Induction of Menstrual Cycle Disturbances during Strenuous Exercise Training J. Clin. Endocrinol. Metab., November 1, 2001; 86(11): 5184 - 5193. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Ichimaru, Y. Mori, and H. Okamura A Possible Role of Neuropeptide Y as a Mediator of Undernutrition to the Hypothalamic Gonadotropin-Releasing Hormone Pulse Generator in Goats Endocrinology, June 1, 2001; 142(6): 2489 - 2498. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Ohkura, T. Tanaka, S. Nagatani, D. C. Bucholtz, H. Tsukamura, K.-I. Maeda, and D. L. Foster Central, But Not Peripheral, Glucose-Sensing Mechanisms Mediate Glucoprivic Suppression of Pulsatile Luteinizing Hormone Secretion in the Sheep Endocrinology, December 1, 2000; 141(12): 4472 - 4480. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Nagatani, Y. Zeng, D. H. Keisler, D. L. Foster, and C. A. Jaffe Leptin Regulates Pulsatile Luteinizing Hormone and Growth Hormone Secretion in the Sheep Endocrinology, November 1, 2000; 141(11): 3965 - 3975. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. C. Bucholtz, A. Chiesa, W. N. Pappano, S. Nagatani, H. Tsukamura, K.-I. Maeda, and D. L. Foster Regulation of Pulsatile Luteinizing Hormone Secretion by Insulin in the Diabetic Male Lamb Biol Reprod, May 1, 2000; 62(5): 1248 - 1255. [Abstract] [Full Text]
|
|
|
|
|
|
B. N. Roy, R. L. Reid, and D. A. Van Vugt The Effects of Estrogen and Progesterone on Corticotropin-Releasing Hormone and Arginine Vasopressin Messenger Ribonucleic Acid Levels in the Paraventricular Nucleus and Supraoptic Nucleus of the Rhesus Monkey Endocrinology, May 1, 1999; 140(5): 2191 - 2198. [Abstract] [Full Text]
|
|
|
|
|
|
D. A. Van Vugt, J. Piercy, A. E. Farley, R. L. Reid, and S. Rivest Luteinizing Hormone Secretion and Corticotropin-Releasing Factor Gene Expression in the Paraventricular Nucleus of Rhesus Monkeys Following Cortisol Synthesis Inhibition Endocrinology, June 1, 1997; 138(6): 2249 - 2258. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | CONTACT US | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
