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Journal of Endocrinology (1956) 14, 263-267    DOI: 10.1677/joe.0.0140263
© 1956 Society for Endocrinology

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THE MELANOPHORE-EXPANDING AND CORTICOTROPHIC ACTIVITY OF HUMAN PITUITARY TISSUE

C. J. O. R. MORRIS, DOROTHY S. RUSSELL, F. W. LANDGREBE and G. M. MITCHELL

Three regions of the human pituitary, viz. (1) anterior lobe, (2) posterior lobe, and (3) intermediate zone (areas of 'basophil cell invasion') in the posterior lobe have been separately assayed for 'B' and corticotrophin in four specimens.

The anterior lobe gave the highest levels for both hormones, the posterior lobe contained little of either, while the intermediate zone (of 'basophil cell invasion') yielded some corticotrophin but significantly high levels of 'B'.

It is suggested that 'B' may be secreted by the {delta} cells and corticotrophin by the β cells of the human pituitary.




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N. Halmi, M. Peterson, G. Colurso, A. Liotta, and D. Krieger
Pituitary intermediate lobe in dog: two cell types and high bioactive adrenocorticotropin content
Science, January 2, 1981; 211(4477): 72 - 74.
[Abstract] [PDF]




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