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The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW 1 2 HE, UK

(Correspondence should be addressed to W H James; Email: whjames{at}waitrose.com)

An attempt is made to summarize the evidence that the offspring sex ratios (proportions male at birth) of mammals (including man) are causally related to the hormone levels of both parents around the time of conception. Almost all of the cited studies were reported by non-endocrinologists. This being so, it would seem desirable to have comments of endocrinologists on this topic. The purpose of this article is to elicit such comment. Readers are requested to read the accompanying editorial (Clark & Davis 2008) to gain a better perspective of this hypothesis article.

This article has been cited by other articles:

				W. H. James The sex ratio of offspring of women with congenital adrenal hyperplasia Hum. Reprod., October 23, 2008; (2008) den370v1. [Full Text] [PDF]

				A J L Clark and J R E Davis J. Endocrinol., July 1, 2008; 198(1): 1 - 1. [Full Text] [PDF]