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It has been shown by now that the oviduct of birds, reptiles and amphibians in vitro gives a contractile reponse to low concentrations of neurohypophysial hormones (for references see Heller, Ferreri & Leathers, 1970). Fishes have been little investigated but it could be shown that the oviduct of some oviparous teleosts and the ovaries of certain ovoviviparous bony fishes are stimulated by vasotocin, ichthyotocin and oxytocin (Heller & Leathers, 1969). Attempts (Dreyer, 1946; Perks, 1959; Dodd, Perks & Dodd, 1966) to demonstrate effects of elasmobranch pituitary extracts or oxytocin on elasmobranch oviducts in vitro were unsuccessful because of persistent, strong, spontaneous contractions. Further experiments on elasmobranch oviducts seemed indicated because of (1) the positive results obtained in the other classes of cold-blooded vertebrates, (2) the possibility of finding a more suitable suspension fluid, (3) the availablity of purified elasmobranch neurohypophysial principles, and (4) a more sensitive method of recording (see