HOME HELP CONTACT US SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by DÖCKE, F. Articles by GLASER, D. Search for Related Content PubMed Articles by DÖCKE, F. Articles by GLASER, D.

Ramirez & Sawyer (1965) demonstrated that in female rats in pro-oestrus, a marked drop in the luteinizing hormone-releasing factor (LH-RF) in the stalk median eminence occurs only after the ovulatory release of LH. The authors postulated that the LH released may inhibit the synthesis of LH-RF by a negative feedback action. If this assumption is correct, artificial maintenance of an increased level of LH in the hypothalamus should suppress the postovulatory increase of LH-RF in the stalk median eminence that was observed by the same authors and is probably necessary for the subsequent ovulation. To test this hypothesis, adult female Wistar rats, exposed to light from 05.00 to 19.00 h, and with regular 4-day cycles were used. They were implanted with intrahypothalamic ovine LH (NIH-LH-S 15) or with cholesterol between 09.00 and 12.00 h on the day of oestrus.

The LH implants were prepared by tamping a 1:1 mixture of