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Laboratorio de Investigaciones Endócrino-Oncológicas, Instituto de Histología y Embriología, Facultad de Ciencias Médicas, U.N.C., 5.500 Mendoza, Argentina

(Received 16 August 1976)

The secretion of prolactin by the pars distalis transplanted at a site remote from the hypothalamus was first reported by Desclin (1950). This author observed the persistence of the ovarian corpora lutea in hypophysectomized, oestrogen-treated rats bearing a pars distalis graft under the kidney capsule. Everett (1954, 1956) confirmed Desclin's findings, but in addition demonstrated that liberation of prolactin from the pituitary gland graft occurred independently of oestrogen. Mühlbock & Boot (1959) found that transplanted hypophyses release prolactin continuously. Chen, Amenomori, Lu, Voogt & Meites (1970) have determined the serum prolactin concentrations, measured by radioimmunoassay, in hypophysectomized, ovariectomized rats with 1, 2 or 4 pars distalis grafts under the kidney capsule. Under these conditions the amount of prolactin released by the transplants was judged to be similar to that