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Rat testicular radioreceptor assays specific for FSH and LH were used to determine the FSH: LH ratio of PMSG produced by horse, donkey, mule and hinny conceptuses. Measurements of FSH and LH activities in PMSG produced both in vivo and in vitro by the four types of conceptuses showed that the genotype of the foetus markedly influences the FSH: LH ratio of PMSG. The FSH: LH ratio of PMSG produced by the horse conceptus was around unity whereas the ratio of PMSG produced by the donkey conceptus was as low as 0·2. Furthermore, the hybrid mule and hinny conceptuses both produced PMSG with an FSH: LH ratio which was approximately midway between those of the horse and donkey.