HOME HELP CONTACT US SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by DENEF, C. Articles by HAUTEKEETE, E. Search for Related Content PubMed Articles by DENEF, C. Articles by HAUTEKEETE, E.

Department of Pharmacology, Fakulteit Geneeskunde, Katholieke Universiteit Leuven, B-3000 Leuven, Belgium

(Received 23 January 1978)

It has been shown that fluctuations in the secretion of follicle-stimulating hormone (FSH), which occur under a variety of physiological and experimental conditions in vivo and are not dependent on the secretion of luteinizing hormone (LH), are closely paralleled by fluctuations in the rate of conversion of testosterone to 5-dihydrotestosterone (DHT) by intact pituitary tissue in vitro (Denef, Magnus & McEwen, 1973, 1974). This suggests that the rate of formation of DHT by the pituitary gland increases when certain independent regulatory mechanisms controlling the release of FSH are activated. Non-parallel changes in the plasma concentrations of FSH and LH in the rat have also been observed after bilateral cryptorchidectomy (Swerdloff, Walsh, Jacobs & Odell, 1971; Gupta, Rager, Zarzycki & Eichner, 1975; Hall & Gomes, 1975; Gomes & Jain, 1976; Ojeda, Jameson & McCann, 1976). Most