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Journal of Endocrinology (1978) 79, 243-244    DOI: 10.1677/joe.0.0790243
© 1978 Society for Endocrinology

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APPEARANCE OF OESTRONE SULPHATE IN THE ALLANTOIC FLUID OF THE COW

H. A. ROBERTSON, G. J. KING and J. A. CARNEGIE

Reproductive Physiology Program, Animal Research Institute, Ottawa, Ontario, Canada, K1A 0C6 and * Department of Animal and Poultry Science, University of Guelph, Guelph, Ontario, Canada, N1G 2W1

(Received 15 May 1978)

The ability of the conceptus to synthesize oestrogens during the early stages of pregnancy has recently been receiving increasing attention. Among the domesticated species, the day 12 blastocyst of the pig has been shown to be capable of synthesizing oestrogens (Perry, Heap & Amoroso, 1973; Gadsby, Burton, Heap & Perry, 1976) and oestrone sulphate, synthesized as a product of conception, has been shown to be present in the peripheral plasma of the pregnant pig as early as day 17 (Robertson & King, 1974; Robertson, King & Dyck, 1978). In the pregnant ewe, oestrone sulphate has been shown to be the predominant oestrogen in allantoic fluid and to be present in measurable concentrations as early as day 30 (Carnegie & Robertson,







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