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The conversion of [4-¹⁴C]progesterone to androstenedione by thecal tissue homogenates from the large yellow follicles of the hen ovary was measured at two periods of the ovulatory cycle after incubation for 1 h in the presence of cofactors. Production of androstenedione by the largest follicle, F1, was reduced significantly 1–2 h before ovulation compared with 15 h before ovulation, whereas production of an unidentified androgen increased. These differences were not observed in the next largest follicles, F2 and F3. Thecal tissue homogenates from all the follicles converted [4-¹⁴C]progesterone to 17 -hydroxyprogesterone, androstenedione and testosterone.

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				T M Lovell, P G Knight, and R T Gladwell Differential expression of mRNAs encoding the putative inhibin co-receptor (betaglycan) and activin type-I and type-II receptors in preovulatory and prehierarchical follicles of the laying hen ovary J. Endocrinol., February 1, 2006; 188(2): 241 - 249. [Abstract] [Full Text] [PDF]