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Aldosterone production by isolated adrenal glomerulosa cells from the rat was estimated in the presence of varying concentrations of sodium ion. The reduction of sodium concentration by 5–20 mmol/l, with or without osmotic changes, did not influence the rate of aldosterone production. Aldosterone response to angiotensin II was not modified by varying the sodium concentration.
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J. K. Makara, G. L. Petheo, A. Toth, and A. Spat Effect of Osmolarity on Aldosterone Production by Rat Adrenal Glomerulosa Cells Endocrinology, May 1, 2000; 141(5): 1705 - 1710. [Abstract] [Full Text] [PDF] |
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