JOE
HOME HELP CONTACT US SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     


Journal of Endocrinology (1981) 90, 315-322    DOI: 10.1677/joe.0.0900315
© 1981 Society for Endocrinology

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by LINTON, E. A.
Right arrow Articles by JEFFCOATE, S. L.
Right arrow Search for Related Content
PubMed
Right arrow Articles by LINTON, E. A.
Right arrow Articles by JEFFCOATE, S. L.

2-HYDROXYOESTRADIOL INHIBITS PROLACTIN RELEASE FROM THE SUPERFUSED RAT PITUITARY GLAND

ELIZABETH A. LINTON, NICKI WHITE, OFELIA LIRA DE TINEO and S. L. JEFFCOATE

The effects of 2-hydroxyoestradiol (2OH-OE2), dopamine, oestradiol-17β and 2OH-OE2 plus dopamine on prolactin and LH release from the male rat pituitary gland were examined in vitro.

2-Hydroxyoestradiol reduced prolactin secretion by 51% at 10–10 mol/l and by 34% at 10–7 mol/l, while oestradiol-17β had no effect at these doses. Dopamine alone (5 x 10–7 mol/l) decreased prolactin released by 58%, 2OH-OE2 plus dopamine produced a similar inhibition of 60%.

No significant effect on LH release was observed throughout.







HOME HELP CONTACT US SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1981 by the Society for Endocrinology.